In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression. SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors. This drug was initially under [...]
Most studies over the last few decades have estimated the prevalence of postpartum depression (PPD) in the United States to be between 10% and 15%. According to longitudinal data derived from the Pregnancy Risk [...]
Many studies have documented the finding that exposure to maternal psychiatric illness early on in the child’s life may adversely affect the child’s cognitive, emotional and behavioral development. These early studies focused on the impact [...]
One of our readers contacted us noting that she developed a severe episode of postpartum depression after receiving an injection of the contraceptive, Depo-Provera. She is pregnant again and now wonders if she should avoid [...]
Although new mothers describe breastfeeding as a meaningful and fulfilling aspect of caring for their infants, breastfeeding is also a common source of stress and anxiety. Breastfeeding self-efficacy or BSE refers to a mother’s confidence [...]
We have seen multiple studies which indicate that postpartum depression (PPD) interferes with breastfeeding. Postpartum women who suffer from depression are less likely to breastfeed, and they typically breastfeed for a shorter duration than women who are not depressed. A recent study looks at an entirely different question, asking whether postpartum stress affects the quality of the breast milk. In this study, the researchers focused on levels of immunoglobulin A (IgA) in the breast milk. (Immunoglobulins or antibodies are passed from the mother to the baby through the breast milk and help to confer immunity.)
Many studies have observed that postpartum depression may negatively affect the mother-infant relationship and may thus impede bonding and attachment and negatively affect the development of the young child. A recent study explores the use of Perinatal Dyadic Psychotherapy (PDP), a dual-focused mother-infant intervention designed to prevent and/or decrease depressive symptoms in the mother and to improve aspects of the mother-infant relationship related to child development.
85 women with postpartum depression were randomized to receive acupuncture plus psychological intervention (five sessions per week) or treatment with fluoxetine (20 mg per day). The two groups were treated continuously for six weeks. Depressive symptoms were measured using the Hamilton Depression scale (HAMD).