Are Women with PMDD at Increased Risk for Suicidality?
In a recent meta-analysis, Yan and colleagues looked at the prevalence of suicidal ideation among women diagnosed with PMDD.
Essential Reads: A Clinical Guide for the Diagnosis and Treatment of PMDD
In an evidence-based review published in 2012, Laura Wakil, Samantha Meltzer-Brody, and Susan Girdler present a thorough review of premenstrual dysphoric disorder (PMDD), reviewing its diagnosis and treatment options.
Internet-Based Cognitive-Behavioural Therapy for Women with PMDD
There is excellent data to support the use of selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs) for the treatment of premenstrual dysphoric disorder (PMDD); however, many women do not want to take [...]
Allopregnanolone Sparks Interest as New PMDD Treatment
Allopregnanolone is all over the place these days. We have seen several different allopregnanolone derivatives being used to treat postpartum depression (PPD). Last year, intravenous brexanolone (Zulresso) was approved by the FDA as the [...]
Psychiatric Illness More Common in Women Undergoing Oophorectomy
Not infrequently we see women who ask about the possibility of oophorectomy (surgical removal of the ovaries) as a means of managing what appears to be a menstrually related mood disorder. While this is an [...]
Brexanolone (Zulresso) for Postpartum Depression Cleared by the DEA, Now Available
Brexanolone, to be marketed by Sage Therapeutics as Zulresso, was initially approved in March 2019, as a treatment for postpartum depression. At that time, we were told that Zulresso would be available in June 2019. [...]
Chasteberry for PMS and PMDD
Chasteberry, the fruit of the chaste tree or Vitex agnus castus, has long been touted as a remedy for a range of reproductive problems, including premenstrual symptoms or PMS. Two recent publications have reviewed data [...]