Sepranolone: A New Treatment for PMDD?
In this phase II study, sepranolone 10 mg administered subcutaneously during the late luteal phase reduced PMDD symptoms more than placebo.
Essential Reads: Is PMDD a Risk Factor for Postpartum Depression?
Some, but not all, studies suggest that PMDD is a risk factor for postpartum depression.
Are Women with PMDD at Increased Risk for Suicidality?
In a recent meta-analysis, Yan and colleagues looked at the prevalence of suicidal ideation among women diagnosed with PMDD.
Essential Reads: A Clinical Guide for the Diagnosis and Treatment of PMDD
In an evidence-based review published in 2012, Laura Wakil, Samantha Meltzer-Brody, and Susan Girdler present a thorough review of premenstrual dysphoric disorder (PMDD), reviewing its diagnosis and treatment options.
Internet-Based Cognitive-Behavioural Therapy for Women with PMDD
There is excellent data to support the use of selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs) for the treatment of premenstrual dysphoric disorder (PMDD); however, many women do not want to take [...]
Psychiatric Illness More Common in Women Undergoing Oophorectomy
Not infrequently we see women who ask about the possibility of oophorectomy (surgical removal of the ovaries) as a means of managing what appears to be a menstrually related mood disorder. While this is an [...]
Brexanolone (Zulresso) for Postpartum Depression Cleared by the DEA, Now Available
Brexanolone, to be marketed by Sage Therapeutics as Zulresso, was initially approved in March 2019, as a treatment for postpartum depression. At that time, we were told that Zulresso would be available in June 2019. [...]
Chasteberry for PMS and PMDD
Chasteberry, the fruit of the chaste tree or Vitex agnus castus, has long been touted as a remedy for a range of reproductive problems, including premenstrual symptoms or PMS. Two recent publications have reviewed data [...]