This article focuses on how GABA-ergic neurotransmitter systems may modulate the interaction between reproductive steroid and sex steroid systems, and sheds light on the role allopregnanolone may play in medicating vulnerability to depression.
Depression During Pregnancy Affect Infant’s Brain Anatomy, But No Change with Prenatal Exposure to SSRIs
Infants exposed to maternal depression during pregnancy had significantly larger subcortical grey matter volumes and smaller midbrain volumes.
There have been multiple studies over last year showing increased anxiety and depression in certain populations as a result of the COVID pandemic. It is clear that some members of the population may be [...]
In a given year, about 10% of mothers in the United States experience a major depressive episode (MDE). Roughly translated, this means about 1 in 10 children is exposed to maternal depression each year (Ertel [...]
In women, testosterone is produced by the ovaries in small amounts; however, levels of testosterone decline with age, independent of menopausal status. Low-dose testosterone has been used to improve sexual functioning in women with [...]
Although it is widely accepted that perimenopausal women are at increased risk for depressive symptoms, little research exploring suicidality in mid-life women has been conducted. In the spirit of Suicide Prevention Month, we will review [...]
Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels
Women are at increased risk for depressive symptoms during the menopause transition. It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience [...]
Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids. This class of compounds are steroid hormones produced in the brain and endocrine tissues which can modulate [...]
Patients and clinicians may not be fully aware that women are at increased risk for depression during the menopausal transition. The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen all adults for [...]
We are deeply troubled by the recent killings of Ahmed Aubrey, Breonna Taylor, George Floyd and other Black Americans. These events bring into sharp focus the long-standing problems of racism, bias, and inequity in our [...]