For women taking antidepressants, how do we decide whether or not they should maintain their medication during pregnancy? Based on our previous research and clinical experiences, we know that many women who discontinue antidepressant therapy [...]
Last week, I met with a woman who was planning pregnancy. She had a long history of generalized anxiety disorder and panic disorder and had done very well over the past 10 years on [...]
From the OptumLabs Data Warehouse, researchers identified 226,932 singleton deliveries. Cases of antidepressant exposure were defined as pregnancies with prescription claims for antidepressants submitted between the last menstrual period and 35 weeks’ gestation. To [...]
While we have data to support the use of antidepressants, including the selective serotonin reuptake inhibitors (SSRIs) and the serotonin norepinephrine reuptake inhibitors (SNRIs), during pregnancy, most studies have focused on risk of congenital [...]
In 2015, the U.S. Food and Drug Administration (FDA) proposed major revisions to prescription drug labeling -- the Pregnancy and Lactation Labeling Rule or PLLR -- in order to provide more accurate and helpful information [...]
A few weeks ago, we published a clinical update for duloxetine (Cymbalta) and pregnancy, stating that there was little new to report since we last covered the topic in 2015. It is somewhat amusing that [...]