Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants.

This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy. For more information, please call 1-866-961-2388 or e-mail

Help make the future better for many other women like you.

The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Can Tofu Reduce Your Risk of Depression During Pregnancy?

    October 26, 2016


    Phytoestrogens are weak plant-derived estrogens that are structurally similar to estrogen hormones produced by the body.  The phytoestrogens contained in soy-based products are called isoflavones.  Because they have estrogenic activity, soy isoflavones have long been touted as a treatment for menopausal symptoms, although these clinical studies have yielded mixed results.   States of estrogen deficiency and ...

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  • What Exactly Causes Hot Flashes in Menopausal Women? Researchers Look at Neurokinin B

    October 25, 2016

    Closeup portrait, morose elderly lady, daydreaming about the future looking ahead, resting face on hand, isolated green trees outdoors background

    Perimenopausal vasomotor symptoms are triggered by a fall in circulating levels of estrogen and other sex steroids. It has been hypothesized that thermoregulatory centres in the hypothalamus play a crucial role in mediating the hot flash response. However, exactly how do hormonal changes bring about these changes in the hypothalamus?  If we could understand this ...

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  • Prenatal Antiepileptic Exposure Increases Risk for Malformations: Does High-Dose Folic Acid Reduce Risk?

    October 24, 2016


    The CDC, the U.S. Public Health Service, and the American College of Obstetricians and Gynecologists (ACOG) all recommend that every woman of reproductive age get 400 micrograms (400 mcg) or 0.4 milligrams of folic acid every day. Most multivitamins contain 400 micrograms or 0.4 milligrams of folic acid. Most prenatal vitamins have approximately 800 micrograms ...

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  • Weekly Roundup for OCT 21 2016: Recent Publications in Women’s Mental Health

    October 22, 2016


    There are lots of new articles to review — partly because I haven’t had a chance to pull together the “weekly” roundup for a while, but also because there continues to be a huge number of articles being published in the field of perinatal psychiatry.  Some of the most interesting articles on the list are ...

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  • Prenatal SSRI Exposure and Speech/Language Disorders: Many Headlines, Little Risk

    October 21, 2016

    African mother and her kids are having fun in the nature

    Last week, an article looking at the cognitive and motor development of children with prenatal exposure to antidepressants was published in JAMA Psychiatry.  Since that time, we have received a lot of questions regarding the article and the clinical implications of its findings.  When I did a quick Google search, I found 36 articles reviewing ...

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  • Press Release: Potential Treatment Option for Women Deciding to Discontinue Antidepressants During Pregnancy

    October 18, 2016

    Cute expectant mother is very tired. She is sitting on couch. Her eyes are closed with relaxation

    Massachusetts General Hospital Efficacy Study Centers on EnBrace HR™ SUNSET, LA (PRWEB) OCTOBER 18, 2016: JayMac Pharmaceuticals is sponsoring a study at Massachusetts General Hospital to assess the efficacy of a pre-and post-natal supplement, EnBrace HR™, as a treatment for the prevention of depression in women with a history of Major Depressive Disorder who decide to discontinue ...

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